Tesamorelin
Growth-hormone and fat-metabolism research · From $55
Overview
Tesamorelin is a synthetic analogue of the full-length 44-residue human growth hormone-releasing factor, modified by acylation of the N-terminal tyrosine with a trans-3-hexenoyl group, a substitution studied for its effect on resistance to N-terminal proteolytic degradation. In preclinical and mechanistic literature it is investigated as a tool compound for probing GHRH-receptor signalling and the downstream GH/IGF-1 axis, including transcriptomic and adipose-tissue studies in animal and human research cohorts.
- Purity
- ≥ 99%
- Form
- Lyophilized powder
- Class
- N-terminally trans-3-hexenoylated GHRH(1-44) amide
- Storage
- −20 °C, desiccated, dark
Also known as TH9507, TH-9507, Tesamorelin acetate.
Research explained
The research interest
How this compound fits into growth-hormone research.
What was studied
A preclinical source has yet to be selected for this short summary.
Evidence context
The source selection for this summary is incomplete. That describes this page's coverage, not the entire research record.
Selected-source check, not a complete clinical review. No human-use recommendation.
Structure
Specifications
Identity
- CAS number
- 218949-48-5
- Formula
- C221H366N72O67S
- Molecular weight
- 5135.9 g/mol
- Chain length
- 44 residues
Material
- Purity, RP-HPLC
- ≥ 99%
- Form
- Lyophilized powder
- Appearance
- White to off-white lyophilized powder (commonly supplied as the acetate salt)
- Vial sizes
- 5 mg, 10 mg
Handling
- Solubility
- Soluble in water and in dilute aqueous acetic acid; compatible with DMSO for preparation of laboratory stock solutions. Contains an oxidation-sensitive methionine residue, so oxidising conditions are avoided during handling.
- Storage
- Lyophilized powder: store at -20 °C, desiccated and protected from light; -80 °C for long-term storage. Solutions: aliquot and store at -80 °C; avoid repeated freeze-thaw cycles.
Literature and research use
Literature is cited on each component's own listing.
Citations describe published preclinical and in-vitro findings for this compound class and are not a representation about this material.
Research use only
All products listed on this site are supplied strictly as chemical reference materials for in-vitro laboratory research and are labelled For Research Use Only. They are not drugs, foods, cosmetics, or medical devices. They are not intended to diagnose, treat, cure, or prevent any condition, and are not for human or veterinary consumption or administration under any circumstances.
Research use policy ›$55
$11.00 per mg
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