BPC-157
Tissue-repair and blood-vessel research · From $50
Overview
BPC-157 is a synthetic pentadecapeptide corresponding to a partial sequence of a protein isolated from human gastric juice. It is investigated in preclinical rodent and in-vitro models as a probe of angiogenic and cytoprotective signalling, with reported literature endpoints including tendon fibroblast outgrowth and migration, VEGFR2/eNOS pathway modulation, and intestinal epithelial barrier permeability.
- Purity
- ≥ 99%
- Form
- Lyophilized powder
- Class
- Pentadecapeptide
- Storage
- −20 °C, desiccated, dark
Also known as Body Protection Compound-157, PL-14736, PLD-116.
Research explained
The research interest
How tendon cells move and respond to stress.
What was studied
It tested cells taken from rat tendons, including how they moved and survived stress.
Evidence context
The selected source examines rat tendon cells. Its scope is cell behaviour in a laboratory.
Selected-source check, not a complete clinical review. No human-use recommendation.
Structure
Specifications
Identity
- CAS number
- 137525-51-0
- Formula
- C62H98N16O22
- Molecular weight
- 1419.5 g/mol
- Chain length
- 15 residues
Material
- Purity, RP-HPLC
- ≥ 99%
- Form
- Lyophilized powder
- Appearance
- White to off-white lyophilized powder
- Vial sizes
- 5 mg, 10 mg
Handling
- Solubility
- Soluble in water and aqueous buffers; also soluble in DMSO. Laboratory solvent compatibility only.
- Storage
- Lyophilized powder stored at -20 °C, desiccated and protected from light; long-term storage at -80 °C. In solution, store at -20 °C and avoid repeated freeze-thaw cycles.
Literature and research use
- The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migrationPMID 21030672 · 2011
- Stable Gastric Pentadecapeptide BPC 157 and Wound HealingPMID 34267654 · 2021
- BPC 157 Rescued NSAID-cytotoxicity Via Stabilizing Intestinal Permeability and Enhancing CytoprotectionPMID 32445447 · 2020
Citations describe published preclinical and in-vitro findings for this compound class and are not a representation about this material.
Research use only
All products listed on this site are supplied strictly as chemical reference materials for in-vitro laboratory research and are labelled For Research Use Only. They are not drugs, foods, cosmetics, or medical devices. They are not intended to diagnose, treat, cure, or prevent any condition, and are not for human or veterinary consumption or administration under any circumstances.
Research use policy ›$50
$10.00 per mg
- In stock · Certificates ›